Jorge Martín suffered a collarbone fracture during the Sprint race at the Japanese Grand Prix.
The crash occurred at Turn 1, where he lost control of his Aprilia and collided with Marco Bezzecchi.
Both riders were subsequently taken to the medical centre for evaluation. Bezzecchi was cleared to race, but Martín was diagnosed with a broken collarbone and is scheduled for surgery.
This injury adds to a series of setbacks for the reigning MotoGP World Champion, who has faced multiple crashes and injuries throughout the season.